Patent · US Active

Compositions for diagnosis and therapy of diseases associated with aberrant expression of futrins (R-spondins) and/or Wnt

US9081011B2 · kind B2 · utility

0Cited by

13References

14Claims

0Family size

Assignee

Deutsches Krebsforschungszentrum · DE

Inventors

Christof Niehrs · Heidelberg, DE
Wei Wu · Beijing, CN
Andrey Glinka · Edingen-Neckarhausen, DE
Olga Kazanskaya · Heidelberg, DE

Key dates

Filing date	Oct 8, 2004
Grant date	Jul 14, 2015
Priority date	—
Expiry date	Dec 23, 2029

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/10
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to a composition useful for the diagnosis of diseases associated with aberrant expression of the genes encoding the secreted proteins Futrin 1, 2, 3 and/or 4(=R-Spondin 2, 3, 1 and 4, respectively), e.g. in connection with tumors or diseases of the muscle, kidneys or bones. The present invention also relates to a pharmaceutical composition containing a compound which is capable of modifying (a) the expression of the gene encoding Futrin 1, 2, 3 and/or 4 or (b) the activity of the Futrin 1, 2, 3 and/or 4 protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.