Patent · US Active

Assay for measurement of antibodies binding to a therapeutic monoclonal antibody

US9081016B2 · kind B2 · utility

0Cited by

22References

9Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Veit Peter Grunert · Munich, DE
Ursula Klause · Peißenberg, DE
Pavel Kubalec · Feldafing, DE
Matthias Rothfuss · Penzberg, DE
Barbara Upmeier · Iffeldorf, DE

Key dates

Filing date	Feb 13, 2013
Grant date	Jul 14, 2015
Priority date	—
Expiry date	Feb 13, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/52
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods and system for determination of an anti-<therapeutic monoclonal antibody> antibody (anti-<TmAB>AB) in vitro in a sample from a patient treated with a therapeutic monoclonal antibody (TmAB). Also, methods and systems for the determination of antigen specific antibodies of a particular immunoglobulin class and for the identification of a patient who is at risk of developing an adverse drug reaction (ADR) during treatment with a TmAB.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.