Patent · US Active

Compositions and methods for prevention of escape mutation in the treatment of HER2/NEU over-expressing tumors

US9084747B2 · kind B2 · utility

16Cited by

9References

25Claims

0Family size

Assignees

Advaxis, Inc. · US
The Trustees of the University of Pennsylvania · US

Inventors

Vafa Shahabi · Valley Forge, US
Anu Wallecha · Yardley, US
Paulo Maciag · Long Grove, US
Yvonne Paterson · Philadelphia, US
Matthew Seavey · Secane, US

Key dates

Filing date	Nov 12, 2010
Grant date	Jul 21, 2015
Priority date	—
Expiry date	Sep 19, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/523
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention provides compositions and methods for treating and vaccinating against an Her2/neu antigen-expressing tumor and inducing an immune response against dominant and several sub-dominant epitopes of the antigen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.