Method for extracting and separating ginkgolides
US9084755B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 23, 2014 |
| Grant date | Jul 21, 2015 |
| Priority date | — |
| Expiry date | Oct 23, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2236/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for extracting and separating ginkgolides. The ginkgolides obtained through steps of extraction on a ginkgo leaf, further extraction, column chromatography, crystallization, and crystal mixing comprise 25.0% to 50.0% of bilobalide (C15H18O8), 20.0% to 45.0% of ginkgolide A (C20H24O9), 10.0% to 30.0% of ginkgolide B (C20H24O10), and 5.0% to 15.0% of ginkgolide C (C20H24O11). The total quantity of the bilobalide, the ginkgolide A, the ginkgolide B, and the ginkgolide C is over 95%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.