Magnetic microstructures for magnetic resonance imaging

US9084819B2 · kind B2 · utility

Assignees

• THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · US
• The United States of America, represented by the Secretary of Commerce · US

Inventors

• Gary Zabow · Boulder, US
• Stephen Dodd · Rockville, US
• Alan Korelsky · Kirkwood, US
• John Moreland · Louisville, US

Key dates

• Filing date: Apr 2, 2010
• Grant date: Jul 21, 2015
• Expiry date: Oct 29, 2031

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/2982
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a magnetic resonance structure with a cavity or a reserved space that provides contrast and the additional ability to frequency-shift the spectral signature of the NMR-susceptible nuclei such as water protons by a discrete and controllable characteristic frequency shift that is unique to each MRS design. The invention also relates to nearly uniform solid magnetic resonance T2* contrast agents that have a significantly higher magnetic moment compared to similarly-sized existing MRI contrast agents.