Composition for treating diabetes and metabolic diseases and a preparation method thereof
US9085520B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Aug 8, 2012 |
| Grant date | Jul 21, 2015 |
| Priority date | — |
| Expiry date | Aug 8, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a chalcone composition for treating diabetes and metabolic syndromes. In particular, the chalcone compound bound with 2-halogen in ring A significantly decreases the blood glucose level in the in vitro anti-diabetic effect experiment. In the in vivo animal model, the leading chalcone compound can prevent the progression of diabetes and control the blood glucose level, and there is no significant difference in the gains in body weight. Throughout the seven-week administration, there are no hepatic or renal toxicity observed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.