Method and substances for the preparation of N-substituted pyridinium compounds

US9085535B2 · kind B2 · utility

Assignee

• Roche Diagnostics Operations, Inc. · US

Inventors

• Dieter Heindl · Munich, DE
• Peter Gebauer · Troisdorf, DE

Key dates

• Filing date: Jan 27, 2012
• Grant date: Jul 21, 2015
• Expiry date: Jan 27, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/80
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Methods for the synthesis of N-substituted carboxylated pyridinium compounds by reaction of a pentamethine precursor with a primary amine are provided. In this reaction an N-substituted alkoxycarbonyl pyridinium heterocycle is formed.