Patent · US Active

Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response

US9085567B2 · kind B2 · utility

1Cited by
5References
7Claims
0Family size

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Key dates

Filing dateFeb 12, 2014
Grant dateJul 21, 2015
Priority date
Expiry dateFeb 12, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds, that are N-alkyl-2-(1-(5-substituted-2-(3-oxo-3-(trifluoromethylsulfonamido)propyl)benzyl)pyrrolidin-2-yl)oxazole-4-carboxamide wherein the 5 substituent is selected from the group consisting of halo and alkyloxy radicals. The compound may be represented by the following formulawherein R1 is selected from the group consisting of CO2R7 and CON(R7)SO2R7 wherein R1, R2, R3, R4, and R7 are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, EP3, TP and/or EP4 receptor mediated diseases or conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.