Anti-TNF antibody formulations

US9085619B2 · kind B2 · utility

Assignee

• AbbVie Biotechnology Ltd. · BM

Inventors

• Wolfgang Fraunhofer · Gurnee, US
• Annika Bartl · Ludwigshafen, DE
• Hans-Juergen Krause · Havelsee, DE
• Markus Tschoepe · Heßheim, DE

Key dates

• Filing date: Oct 3, 2014
• Grant date: Jul 21, 2015
• Expiry date: Oct 3, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may have low levels of conductity resulting from the low levels of ionic excipients. Also included in the invention are formulations comprising water and proteins having low osmolality.