Expression system with SAR element from IFNα2
US9085627B2 · kind B2 · utility
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Key dates
| Filing date | Mar 20, 2012 |
| Grant date | Jul 21, 2015 |
| Priority date | — |
| Expiry date | Mar 20, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A short human genomic nucleotide sequence from the SAR3 region of the human interferon α2 gene permits enhances expression stability in the absence of drug selection and permits generation of stable clones or stable pools of cells for producing recombinant proteins. Although stable clones may be generated, the ability to generate stable pools reduces the burden of generating stable clones.
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