Methods of using compositions comprising variants and fusions of FGF19 polypeptides for reducing glucose levels in a subject
US9089525B1 · kind B1 · utility
37Cited by
52References
91Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 6, 2015 |
| Grant date | Jul 28, 2015 |
| Priority date | — |
| Expiry date | Feb 6, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/66
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21), and variants or fusions of fibroblast growth factor 19 (FGF19) and/or fibroblast growth factor 21 (FGF21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.