Patent · US Active

1,2,6-substituted benzimidazoles as flap modulators

US9089569B2 · kind B2 · utility

3Cited by

3References

13Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Wenying Chai · San Diego, US
Curt A. Dvorak · Poway, US
Wendy Eccles · San Diego, US
James P. Edwards · San Diego, US
Steven Goldberg · Encinitas, US
Paul J. Krawczuk · San Diego, US
Alec D. Lebsack · San Diego, US
Jing Liu · San Diego, US
Daniel J. Pippel · Del Mar, US
Zachary S. Sales · Escondido, US
Virginia M. Tanis · Carlsbad, US
Mark S. Tichenor · San Diego, US
John J. M. Wiener · San Diego, US

Key dates

Filing date	Dec 29, 2014
Grant date	Jul 28, 2015
Priority date	—
Expiry date	Dec 29, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compounds of Formula (I),and solvates, hydrates, and pharmaceutically acceptable salts thereof, wherein X1, X1′, X1″, R1, R2 and R3 are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.