Patent · US Active

Controlled release formulations of levodopa and uses thereof

US9089607B2 · kind B2 · utility

5Cited by

5References

56Claims

0Family size

Assignee

Impax Laboratories, LLC · US

Inventors

Ann Hsu · Los Altos Hills, US
Jim H. Kou · San Jose, US
Laman Alani · Morristown, US

Key dates

Filing date	May 22, 2013
Grant date	Jul 28, 2015
Priority date	—
Expiry date	Sep 6, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C229/36
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The current invention provides a controlled release oral solid formulation of levodopa comprising levodopa, a decarboxylase inhibitor, and a carboxylic acid. Also provided by this invention is multiparticulate, controlled release oral solid formulations of levodopa comprising: i) a controlled release component comprising a mixture of levodopa, a decarboxylase inhibitor and a rate controlling excipient; ii) a carboxylic acid component; and iii) an immediate release component comprising a mixture of levodopa and a decarboxylase inhibitor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.