Piperazino-dihydrothienopyrimidine derivatives

US9090626B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Pascale Pouzet · Biberach, DE
• Christoph Hoenke · Ingelheim am Rhein, DE
• Peter Nickolaus · Warthausen, DE
• Rolf Goeggel · Ulm, DE
• Thomas Fox · Biberach, DE
• Dennis Fiegen · Biberach an der Riß, DE
• Klaus Klinder · Oggelshausen, DE

Key dates

• Filing date: Jun 6, 2013
• Grant date: Jul 28, 2015
• Expiry date: Nov 15, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for treating diseases associated with the inhibition of phosphodiesterase 4 (PDE4) enzyme in a patient comprising administering to the patient in need thereof a therapeutically effective amount of a dihydrothienopyrimidinesulphoxide of formula 1, as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof