Patent · US Active

Macrocyclic FLT3 kinase inhibitors

US9090630B2 · kind B2 · utility

2Cited by
4References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 28, 2012
Grant dateJul 28, 2015
Priority date
Expiry dateSep 28, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D498/18
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to macrocylic compounds and compositions containing said compounds acting as kinase inhibitors, in particular as inhibitors of FLT3 (FMS-Related Tyrosine kinase 3). Moreover, the present invention provides processes for the preparation of the disclosed compounds, as well as methods of using them, for instance as a medicine, in particular for the treatment of cell proliferative disorders, such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.