Method for producing antibody directed against protein expressed on cell surface
US9090672B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 7, 2009 |
| Grant date | Jul 28, 2015 |
| Priority date | — |
| Expiry date | Apr 4, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B30/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed is a method for producing an antibody directed against a protein, particularly a transmembrane protein, expressed on the surfaces of cells.Specifically disclosed is a means for obtaining a desired antibody by mixing cells capable of expressing an antigen protein on the surfaces thereof (i.e., antigen molecule-expressing cells) with an antibody library composed of antibody-expressing cells, viruses or the like, and subsequently concentrating/isolating only components (e.g., antibody-expressing cells, viruses) capable of binding to the antigen molecule-expressing cells from the components (e.g., antibody-expressing cells, viruses) of the antibody library.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.