Anti Notch-1 antibodies
US9090690B2 · kind B2 · utility
1Cited by
38References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 16, 2010 |
| Grant date | Jul 28, 2015 |
| Priority date | — |
| Expiry date | Jun 16, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed toward monoclonal antibodies that bind specifically to Notch1. In one embodiment, the antibodies binds to at least a first epitope and a second epitope, wherein the first epitope resides with the LinA domain of the Notch1 negative regulatory region (NRR), and the second epitope resides within the HD-C domain of the Notch1 NRR.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.