Method of making hydroxyalkylcellulose microparticles
US9090714B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 9, 2013 |
| Grant date | Jul 28, 2015 |
| Priority date | — |
| Expiry date | Sep 9, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2982
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a method of producing hydroxyalkylcellulose microparticles, the method including generating a pulse shock wave, and supplying a hydroxyalkylcellulose aqueous solution to the pulse shock wave generation region, thereby crushing and drying the hydroxyalkylcellulose aqueous solution. According to the production method, hydroxyalkylcellulose microparticles having a volume-average particle size of at least 0.1 μm but less than 15 μm are obtained. By mixing the hydroxyalkylcellulose microparticles with a principal agent and subjecting the resulting mixture to a tablet compression, a solid preparation having excellent tensile strength and disintegration properties can be obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.