Patent · US Active

Sequence of porcine ROSA26 locus and methods of using the same

US9090913B2 · kind B2 · utility

1Cited by

0References

3Claims

0Family size

Assignee

Jiangnan University · CN

Inventors

Qingran Kong · Jingwei, CN
Meiling Wu · Jingwei, CN
Zhonghua Liu · Wuxi, CN

Key dates

Filing date	May 4, 2013
Grant date	Jul 28, 2015
Priority date	—
Expiry date	May 4, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H21/04
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention provides a 5 kb sequence of porcine ROSA26 locus, which can be used for site-specific integration of an exogenous gene into a pig genome. The present invention also provides a gene targeting vector with a 3′ and 5′ arm of the porcine ROSA26 sequence, wherein a target gene can be inserted between the 3′ and 5′ arm sequence. The gene targeting vector can be used to generate transgenic pigs with stable and ubiquitous expression of the target gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.