Biomarker DACT1 for gastric cancer
US9090944B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Dec 16, 2011 |
| Grant date | Jul 28, 2015 |
| Priority date | — |
| Expiry date | Jan 21, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for diagnosing and determining prognosis of gastric cancer in a subject by detecting suppressed expression of the DACT1 gene, which in some cases is due to elevated methylation level in the genomic sequence of this gene. A kit and device useful for such a method are also provided. In addition, the present invention provides a method for treating gastric cancer by increasing DACT1 gene expression or activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.