Serial-line-scan-encoded multi-color fluorescence microscopy and imaging flow cytometry
US9091654B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 6, 2014 |
| Grant date | Jul 28, 2015 |
| Priority date | — |
| Expiry date | Feb 8, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6421
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system for performing high-speed, high-resolution imaging cytometry includes a scanning region that is illuminated by light including at least first and second wavelength bands. The system also includes a cell transport mechanism that transports a cell through the scanning region such that the cell is illuminated. The system further includes a set of at least one linear light sensor, and an optical system that selectively directs light emitted from the cell to two portions of the linear light sensor set such that emitted light in a third wavelength band is primarily directed to a first portion of the linear light sensor set, and emitted light in a fourth wavelength band is primarily directed to a second portion of the linear light sensor set. The system repeatedly takes readings of light falling on the linear light sensor set while the cell is transported through the scanning region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.