Patent · US Active

Method for inducing protein aggregation using a polypeptide with an aggregation region

US9095556B2 · kind B2 · utility

1Cited by

19References

11Claims

0Family size

Assignees

VIB VZW · BE
VRIJE UNIVERSITEIT BRUSSEL · BE

Inventors

Joost Schymkowitz · Meensel-Kiezegem, BE
Frederic Rousseau · Fontenay-le-Fleury, FR

Key dates

Filing date	Jun 20, 2008
Grant date	Aug 4, 2015
Priority date	—
Expiry date	Jan 15, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/735
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention belongs to the field of functional proteomics and, more particularly, to the field of protein aggregation. Described are methods for interfering with the function of a target protein and uses a non-naturally, user-designed molecule, designated as interferor, that has a specificity for a target protein and that induces aggregation upon contact with the target protein. The invention also discloses such interferer molecules and their use in therapeutic applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.