Patent · US Active

Therapeutic and vaccine polyelectrolyte nanoparticle compositions

US9095568B2 · kind B2 · utility

3Cited by
3References
7Claims
0Family size

Inventors

Key dates

Filing dateSep 26, 2008
Grant dateAug 4, 2015
Priority date—
Expiry dateNov 22, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2039/6093
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Polyelectrolyte nanoparticle compositions for biomedical applications are provided comprising at least two carrier domains comprising multivalent ionic domains and an agent exhibiting biological activity when contained within the nanoparticle or on the nanoparticle surface. The multivalent ionic domains may be contained in two separate molecules or in separate but linked domains of a single molecule. The nanoparticle optionally can further comprise an exposed targeting ligand and/or protective surface. The nanoparticle can be contacted to cells or administered directly to an animal for biomedical applications including therapeutics and immune response. The nanoparticle may alternatively be comprised of a carrier material capable of delivering various medically important antigens as vaccine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.