Patent · US Active

O-(substituted benzyl) phosphoramidate compounds and therapeutic use

US9095599B2 · kind B2 · utility

14Cited by

1References

19Claims

0Family size

Assignee

Nanjing Molecular Research, Inc. · CN

Inventors

Junbiao Chang · Zhengzhou, CN
Zheng Wang · 安丰镇, CN
Suping Zhou · Philadelphia, US

Key dates

Filing date	Dec 30, 2011
Grant date	Aug 4, 2015
Priority date	—
Expiry date	Dec 30, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H19/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This application discloses novel phosphoramidate and phosphonoamidate prodrugs of nucleosides, nucleotides, C-nucleosides, C-nucleotides, phosphonates, and other alcohol-containing drugs; use of these prodrugs for treatment of infectious diseases and cancers, in particular, liver infections and cancers; and methods of preparing these novel phosphoramidate and phosphonoamidate prodrugs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.