UV stable transdermal therapeutic plaster with a UV absorbing self-adhesive layer separated from the drug matrix

US9095691B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Jochen Schumacher · Jena, DE
• Manfred Suesse · Langenorla, DE
• Michael Dittgen · Apolda, DE
• Stephan Mletzko · Berlin, DE
• Jan-Peter Ingwersen · Berlin, DE
• Thomas Langguth · Jena, DE
• Dirk Schenk · Dietramszell, DE
• Hubert Kaffl · Munich, DE

Key dates

• Filing date: Mar 15, 2013
• Grant date: Aug 4, 2015
• Expiry date: Jul 10, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/22
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a UV stable transdermal therapeutic system (TTS) consisting of a back layer, at least one matrix containing an active substance and optionally, a withdrawal film and an UV-radiation absorber. An adhesive layer containing said UV-radiation absorber is arranged between the back layer and the matrix containing an active substance which is distant as much as possible from a surface, a separation layer is arranged between the adhesive layer containing said UV-radiation absorber and the matrix containing an active substance, which is as remote as possible from the surface which is impermeable to the active substance and UV-radiation absorber. The inventive transdermal therapeutic system exhibits a high stability and is devoid of inconveniences of existing TTS containing a light-sensitive substance.