Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments

US9096579B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Georg Dahmann · Biberach an der Riß, DE
• Horst Dollinger · Schemmerhofen, DE
• Christian Gnamm · Biberach an der Riß, DE
• Dennis Fiegen · Biberach an der Riß, DE
• Matthias Hoffmann · Mittelbiberach, DE
• Jasna Klicic · Biberach an der Riß, DE
• David James LAMB · Mittelbiberach, DE
• Andreas Schnapp · Biberach, DE

Key dates

• Filing date: Apr 17, 2013
• Grant date: Aug 4, 2015
• Expiry date: Oct 3, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new amino-indole-substituted imidazolyl-pyrimidines of formula 1whereinR1, R2, R3, R4 and R5 are defined as in claim 1 and pharmaceutically acceptable salts thereof and the use of these compounds for the preparation of a medicament for treating a disease selected from asthma, COPD, rheumatoid arthritis, specific lymphomas and specific diseases of the nervous system.