Detection of toxigenic strains of Clostridium difficile
US9096638B2 · kind B2 · utility
3Cited by
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15Claims
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Key dates
| Filing date | Sep 3, 2008 |
| Grant date | Aug 4, 2015 |
| Priority date | — |
| Expiry date | Jan 27, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2561/113
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Primers and probes for detection of toxin-producing (toxigenic) strains of Clostridium difficile, and to methods of detecting toxigenic strains using these primers and probes. Toxigenic strains of C. difficile are detected by nucleic acid-based amplification methods using particular primers and probes that bind to the toxin B (TcdB) gene. These primers and probes are used to amplify C. difficile nucleic acids in clinical samples to determine the presence of these toxigenic strains.
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