Patent · US Active

17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-methylene oxyalkylene aryl derivatives, process for preparation thereof, and use thereof for treatment of diseases

US9096640B2 · kind B2 · utility

0Cited by

31References

12Claims

0Family size

Assignee

Bayer Intellectual Property GmbH · DE

Inventors

Ulrich Klar · Berlin, DE
Wolfgang Schwede · Berlin, DE
Carsten Möller · Berlin, DE
Andrea Rotgeri · Berlin, DE
Wilhelm Bone · Berlin, DE

Key dates

Filing date	Jul 7, 2010
Grant date	Aug 4, 2015
Priority date	—
Expiry date	Oct 15, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/573
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to 17-hydroxy-17-pentafluoroethylestra-4,9(10)-diene-11-methyleneoxyalkylenearyl derivative of the formula I with progesterone-antagonising action and to processes for preparation thereof, to use thereof for treatment and/or prophylaxis of disorders and to the use thereof for production of medicaments for treatment and/or prophylaxis of disorders, especially of fibroids of the uterus (myomas, uterine leiomyomas), endometriosis, heavy menstrual bleeds, meningiomas, hormone-dependent breast cancers and complaints associated with the menopause, or for fertility control and emergency contraception.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.