Non-fouling, anti-microbial, anti-thrombogenic graft-from compositions
US9096703B2 · kind B2 · utility
18Cited by
33References
25Claims
0Family size
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Key dates
| Filing date | Jun 9, 2011 |
| Grant date | Aug 4, 2015 |
| Priority date | — |
| Expiry date | Apr 13, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T442/60
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
A method for preparing and resulting articles of manufacture comprising a substrate having a surface, a bulk beneath the surface, and a grafted polymer layer on the substrate surface, the substrate surface and the grafted polymer layer, in combination, constituting a modified surface having a fibrinogen adsorption of less than about 125 ng/cm2 in a fibrinogen binding assay in which the modified surface is incubated for 60 minutes at 37° C. in 70 μg/mL fibrinogen derived from human plasma containing 1.4 μg/mL I-125 radiolabeled fibrinogen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.