Recombinant microorganisms comprising thioesterase and lysophosphatidic acid acyltransferase genes for fatty acid production
US9096834B2 · kind B2 · utility
1Cited by
28References
32Claims
0Family size
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Key dates
| Filing date | Feb 24, 2012 |
| Grant date | Aug 4, 2015 |
| Priority date | — |
| Expiry date | Feb 24, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y203/01051
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides for the improved production of fatty acid products in a recombinant microorganism or host cell engineered to express a non-native gene encoding a thioesterase and a non-native gene encoding a lysophosphatidic acid acyltransferase (LPAAT), in which the LPAAT is overexpressed in the recombinant microorganism compared to an otherwise identical microorganism that does not include the non-native LPAAT gene. The invention also provides methods of producing fatty acid products using such recombinant microorganisms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.