Patent · US Active

Set of probes for the detection and typing of 46 human papillomavirus mucosal types

US9096910B2 · kind B2 · utility

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6Claims

0Family size

Inventors

Alberto Severini · Edmonton, CA
Vanessa Goleski · Winnipeg, CA

Key dates

Filing date	Jan 29, 2011
Grant date	Aug 4, 2015
Priority date	—
Expiry date	Sep 24, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/708
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

We have developed a set of probes to detect and identify 46 types of mucosal human papillomaviruses (HPV). These probes recognize the variable region comprised between the 2 conserved regions of the published GP5+/GP6+ set of PCR primers. The 46 probes have been shown to hybridize, as intended, to the DNA derived from the following HPV types: 6, 11, 13, 16, 18, 26, 30, 31, 32, 33, 35, 39, 40, 42, 43, 44, 45, 51, 52, 53, 54, 56, 58, 59, 61, 62, 66, 67, 68, 69, 70, 71, 72, 73, 74, 81, 82, 83, 84, 85, 86, 87, 89, 90, 91 and 97. The hybridization of each probe is specific for each type without any cross hybridization among types and it is sensitive enough to allow detection of PCR products for genotyping of HPV DNA contained in clinical samples.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.