Kinase inhibitors, prodrug forms thereof and their use in therapy
US9101632B2 · kind B2 · utility
1Cited by
0References
17Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 2, 2010 |
| Grant date | Aug 11, 2015 |
| Priority date | — |
| Expiry date | Dec 30, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides kinase inhibitors of Formula I: Also provided are reductive prodrugs, comprising a kinase inhibitor as defined above and a reductive trigger linked directly or indirectly to a nitrogen of the kinase inhibitor. Further provided are pharmaceutical compositions, comprising the kinase inhibitors or the prodrugs, and the use of such compositions in therapy, in particular for treating cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.