Inhibitors of filovirus entry into host cells
US9101635B2 · kind B2 · utility
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Key dates
| Filing date | Jul 10, 2010 |
| Grant date | Aug 11, 2015 |
| Priority date | — |
| Expiry date | Jan 7, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Organic compounds showing the ability to inhibit viral glycoprotein (GP)-mediated entry of a filovirus into a host cell are disclosed. The disclosed filovirus entry inhibitor compounds are useful for treating, preventing, or reducing the spread of infections by filovirus including the type species Marburg virus (MARV) and Ebola virus (EBOV). Preferred inhibitors of the invention provide therapeutic agents for combating the Ivory Coast, Sudan, Zaire, Bundibugyo, and Reston Ebola virus strains.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.