Methods and compositions related to clot binding compounds
US9101671B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 31, 2007 |
| Grant date | Aug 11, 2015 |
| Priority date | — |
| Expiry date | Jul 13, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compositions and methods related to clot binding compounds. For example, disclosed are conjugates comprising a surface molecule and a plurality of clot binding compounds. The clot binding compounds can selectively bind to clotted plasma protein. The conjugate can, for example, cause clotting and amplify the accumulation of the conjugate in tumors. In one example, the conjugate can comprise a sufficient number and composition of clot binding compounds such that the conjugate causes clotting and amplifies the accumulation of the conjugate in tumors. The disclosed targeting is useful for treatment of cancer and other diseases and disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.