Patent · US Active

Process for the preparation of retigabine

US9102593B2 · kind B2 · utility

0Cited by

2References

20Claims

0Family size

Assignee

Glaxo Group Limited · GB

Inventors

Russ N. Fitzgerald · Morrisville, US
Alan Millar · Holly Springs, US
Jennifer Fell Toczko · Morrisville, US

Key dates

Filing date	Jan 16, 2012
Grant date	Aug 11, 2015
Priority date	—
Expiry date	Jan 16, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C269/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.