Compounds for stabilizing ryanodine receptors from aberrant levels of calcium release
US9102645B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Mar 14, 2014 |
| Grant date | Aug 11, 2015 |
| Priority date | — |
| Expiry date | Mar 17, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D407/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are methods and compositions comprising compounds capable of normalizing neuronal calcium dyshomeostasis. Also disclosed are methods comprising these compounds for treating neuronal or neurological disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, fronto-temporal dementia, Pick's disease, chronic traumatic encepholopathy, traumatic brain injury, stroke, cerebellar ataxia, multiple sclerosis, Down syndrome, and aging-related CNS disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.