17-hydroxy-17-pentafluoroethyl-estra-4,9(10)-diene-11-ethynylphenyl derivatives, methods for the production thereof and use thereof for treating diseases

US9102701B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Ulrich Klar · Berlin, DE
• Wolfgang Schwede · Berlin, DE
• Carsten Möller · Berlin, DE
• Andrea Rotgeri · Berlin, DE
• Wilhelm Bone · Berlin, DE

Key dates

• Filing date: Jul 8, 2010
• Grant date: Aug 11, 2015
• Expiry date: Oct 24, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J43/003
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to 17-hydroxy-17-pentafluoroethylestra-4,9(10)-diene 11-ethynylphenyl derivatives of the formula I, in which R1 and X are each as defined in the claims and the description,and to a process for preparation thereof and to the use thereof as medicaments.