Patent · US Active

Insulin-oligomer conjugates, formulations and uses thereof

US9102758B2 · kind B2 · utility

0Cited by

229References

8Claims

0Family size

Assignee

Biocon Ltd. · IN

Inventors

Balasingam Radhakrishnan · Chapel Hill, US
Diti Aggarwal · Raleigh, US
Michelle Ferro · Raleigh, US
Kenneth D. James · Reading, GB
Navdeep B. Malkar · Cary, US
Mark A. Miller · Whitemarsh, US
Monica Puskas · Spring Hope, US
Nnochiri Ekwuribe · Cary, US

Key dates

Filing date	Jan 18, 2011
Grant date	Aug 11, 2015
Priority date	—
Expiry date	Feb 22, 2034

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An insulin conjugate is disclosed in which insulin is coupled to a modifying moiety of the formula X—R1—Y-PAG-Z—R2 wherein X, Y, and Z are linking groups, R2 is a capping group, and PAG is a carbon chain that incorporates one or more alkylene glycol moieties.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.