Patent · US Active

Fluorescence axial localization with nanometer accuracy and precision

US9103784B1 · kind B1 · utility

4Cited by

1References

24Claims

0Family size

Assignee

IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. · US

Inventors

Sanjeevi Sivasankar · Ames, US
Hui Li · Regensburg, DE
Chi-Fu Yen · Ames, US

Key dates

Filing date	Nov 15, 2013
Grant date	Aug 11, 2015
Priority date	—
Expiry date	Nov 15, 2033

Classification

Technology area (CPC G)Physics
CPC primaryG02B21/0076
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

We describe a new technique, standing wave axial nanometry (SWAN), to image the axial location of a single nanoscale fluorescent object with sub-nanometer accuracy and 3.7 nm precision. A standing wave, generated by positing an atomic force microscope tip over a focused laser beam, is used to excite fluorescence; axial position is determined from the phase of the mission intensity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.