Solventless mixing process for coating pharmaceutical ingredients
US9107851B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 15, 2012 |
| Grant date | Aug 18, 2015 |
| Priority date | — |
| Expiry date | Dec 22, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a solventless method of producing polymer coated active pharmaceutical ingredient that is taste-masked and may be released in relatively short time. It employs high energy vibrations or acoustic mixing of API particles, water soluble coating material particles and hydrophobic polymer particles, with or without use of other pharmaceutically relevant powders as media. Additionally the method is capable of producing individually coated drug particles without agglomeration or the long drying times associated with solvent based coating methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.