Methods of diagnosing and treating fibrosis
US9107942B2 · kind B2 · utility
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5Claims
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Assignee
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Key dates
| Filing date | Nov 2, 2009 |
| Grant date | Aug 18, 2015 |
| Priority date | — |
| Expiry date | Nov 29, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to methods of diagnosing and treating a fibrotic condition in a mammalian subject. These methods involve measuring the levels of trimethylation at lysine residue 27 of histone-3 and/or measuring the expression levels of EZH2 or YY-1. Agents useful for treating fibrosis or a fibrotic condition are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.