Disubstituted 5-fluoro-pyrimidines

US9108926B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Ulrich Lücking · Berlin, DE
• Dirk Kosemund · Berlin, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Gerhard Siemeister · Berlin, DE
• Ulf Bömer · Glienicke, DE
• Rolf Bohlmann · Berlin, DE

Key dates

• Filing date: Sep 13, 2012
• Grant date: Aug 18, 2015
• Expiry date: Sep 13, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D407/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to disubstituted 5-fluoro-pyrimidines of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).