Heterocycle-functionalized luminogens exhibiting aggregation-induced emission
US9109155B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 24, 2013 |
| Grant date | Aug 18, 2015 |
| Priority date | — |
| Expiry date | Aug 14, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/96469
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The development of a series of fluorescent materials including heterocycle-functionalized luminogens with aggregation-induced/enhanced emission (AIE/AEE), long wavelength emission, and high solid state fluorescence quantum efficiency is contemplated. The described fluorescent materials are promising candidates in selective luminescence-based chemosensor for Hg2+ or ATP, fluorescent staining for mitochondria in living cells with high photostability, stimuli-responsive luminescent materials, and materials for optical waveguides. In addition, these heterocycle-functionalized luminogens are particularly useful as fluorescent labels for biopolymers such as peptides, antibodies, or nucleic acids, making them useful as AIE-active biocompatible probes for clinical cancer imaging and diagnostics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.