Block copolymer having phenylboronic acid group introduced therein, and use thereof
US9114177B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 19, 2012 |
| Grant date | Aug 25, 2015 |
| Priority date | — |
| Expiry date | Nov 19, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G2650/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A block copolymer includes a polyamino acid chain segment and a hydrophilic polymer chain segment. The polyamino acid chain segment includes at least one amino acid residue having a side chain that contains a cationic group and at least one amino acid residue having a side chain that contains a substituted phenylboronic acid group. In the substituted phenylboronic acid group, at least one hydrogen of the phenyl ring is substituted so that the phenylboronic acid group has a pKa of less than 8. Such a block copolymer serves as a carrier that simultaneously imparts stability to a biotechnology-based drug in blood and provides suitable drug-releasing properties of the drug at an affected area.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.