Tetrahydronaphthalenyl compounds useful as sipi agonists
US9115054B2 · kind B2 · utility
10Cited by
11References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 20, 2014 |
| Grant date | Aug 25, 2015 |
| Priority date | — |
| Expiry date | Feb 20, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compounds of Formula (I)and/or a salt thereof; wherein R is —OH or —OP(O)(OH)2. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.