Patent · US Active

Cells expressing modified T cell receptor

US9115372B2 · kind B2 · utility

3Cited by

1References

20Claims

0Family size

Assignees

IMMUNOCORE LIMITED · GB
Adaptimmune Limited · GB

Inventor

Bent Karsten Jakobsen · Abingdon, GB

Key dates

Filing date	Dec 17, 2012
Grant date	Aug 25, 2015
Priority date	—
Expiry date	Sep 16, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2510/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention provides a cell presenting at least one T cell receptor (TCR) anchored to the membrane by a transmembrane sequence, said TCR comprising an interchain disulfide bond between extracellular constant domain residues which is not present in native TCRs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.