Methods for preparing thermally responsive cell culture surfaces
US9116144B2 · kind B2 · utility
1Cited by
25References
8Claims
0Family size
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Key dates
| Filing date | Dec 10, 2012 |
| Grant date | Aug 25, 2015 |
| Priority date | — |
| Expiry date | Apr 19, 2033 |
Classification
- Technology area (CPC D)Textiles; Paper
- CPC primaryD06M2400/01
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A stimuli responsive nanofiber that includes a stimuli responsive polymer, such as a thermally responsive polymer, and a cross-linking agent having at least two latent reactive activatable groups. The nanofiber may also include a biologically active material or a functional polymer. The stimuli responsive nanofiber can be used to modify the surface of a substrate. When the nanofiber includes a thermally responsive polymer, the physical properties of the surface can be controlled by controlling the temperature of the system, thus controlling the ability of the surface to bind to a biologically active material of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.