Method and system for non-invasive assessment of coronary artery disease

US9119540B2 · kind B2 · utility

Assignee

• Siemens Aktiengesellschaft · DE

Inventors

• Puneet Sharma · Rahway, US
• Bogdan Georgescu · Plainsboro, US
• Viorel Mihalef · New Brunswick, US
• Terrence Chen · Princeton, US
• Dorin Comaniciu · Princeton Junction, US

Key dates

• Filing date: Sep 7, 2011
• Grant date: Sep 1, 2015
• Expiry date: Jun 4, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G16H50/50
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

In order to assess coronary artery disease from medical image data, an anatomical model of a coronary artery is generated from the medical image data. A velocity of blood in the coronary artery is estimated based on a spatio-temporal representation of contrast agent propagation in the medical image data. Blood flow is simulated in the anatomical model of the coronary artery using a computational fluid dynamics (CFD) simulation using the estimated velocity of the blood in the coronary artery as a boundary condition.