Gastroretentive dosage forms for doxycycline

US9119793B1 · kind B1 · utility

Assignee

• MEDICON PHARMACEUTICALS, INC. · US

Inventors

• Douglas A. Bakan · Ann Arbor, US
• Waranush Jitpraphai · Chandler, US
• Steven B. Newhard · Scottsdale, US
• Mitchell S. Wortzman · Phoenix, US

Key dates

• Filing date: Jun 28, 2012
• Grant date: Sep 1, 2015
• Expiry date: Jun 28, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/65
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to dosage forms, e.g., swell, float and bioadhesive, and methods that enhance the absorption of doxycycline in the gastrointestinal tract. The oral dosage forms control the spatial and temporal delivery of doxycycline in the gastrointestinal tract. This controlled spatial and temporal delivery provides a site and rate of release, respectively, of the doxycycline into the gastrointestinal tract that enhances the amount of the doxycycline absorbed into the bloodstream.