Live attenuated bordetella strains as a single dose vaccine against whooping cough
US9119804B2 · kind B2 · utility
4Cited by
2References
9Claims
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Key dates
| Filing date | Mar 7, 2007 |
| Grant date | Sep 1, 2015 |
| Priority date | — |
| Expiry date | Nov 19, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.